Introduction
During February 2025 eThekwini District, King Cetshwayo District and Ugu district in KZN has reported cases of HFMD. On 23 February 2025 Buffalo City Metro in the Eastern Cape also confirmed cases of HFMD. HFMD mainly affects infants and children below the ages of 10 years. Fortunately, the HFMD is self-limiting in majority of the cases.
Type of infection
HFMD is a viral infection.
Aetiology
The causative agents are enteroviruses. The most common virus casing HFMD is Coxsackievirus A16
Transmission
- Coming into direct contact with the secretions or the blisters of a patient with HFMD.
- Open coughing and sneezing of the virus into the air.
- Surfaces and other objects like toys may become contaminated by the virus.
- Coming into contact with faeces often infected patient.
Incubation period
3 – 7 days.
Clinical picture
The common signs and symptoms of HFMD are:
- Loss of appetite
- Fever
- Sore throat
- Fatigue
- Small blisters inside of the mouth, sides of the tongue, palms of the hands, and soles of the feet.
- Adults may be asymptomatic.



Prevention
- Practising good hygiene in general
- Regular handwashing
- Not sharing, utensil, toothbrushes and body washing rags.
- Regular cleaning of shared surfaces such as table, sinks and dishes.
Affected community
HFMD mostly affects children in primary schools and daycare centres.
Vaccine
The no vaccine available for HFMD.
Treatment and management
- There is no specific treatment for HFMD but symptomatic treatment.
- Bed rest.
- Proper hydration.
- Symptomatic management of pain and fever.
Affected / Associated Animals
HFMD is not found in any animals.
References
- Nicd.ac.za. [cited 2025 Feb 23]. Available from: https://www.nicd.ac.za/wp-content/uploads/2025/02/HFMD-Factsheet_2025.pdf
- Maryland.gov. [cited 2025 Feb 23]. Available from: https://health.maryland.gov/phpa/IDEHASharedDocuments/hand_foot_mouth_disease.pdf
- Dchealth.dc.gov. [cited 2025 Feb 23]. Available from: https://dchealth.dc.gov/sites/default/files/dc/sites/doh/publication/attachments/HFMD%20Fact%20Sheet.pdf

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